Article

Replication of a GWAS signal near<i>HLA-DQA2</i>with acute myeloid leukemia using a disease-only cohort and external population-based controls

2024-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. Its risk factors include rare and highly penetrant somatic mutations. Genome-wide association studies (GWAS) have also identified four common inherited variants associated with AML risk, but these findings have not yet been confirmed in many independent datasets. Here, we performed a replication study with 567 AML c...

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Literature Corpus work: ab64122c-4432-5f64-bb0e-8e9dfc42f1af
DOI: 10.1101/2024.09.26.24314422

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