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Article

Uncovering Putative Causal Non-coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study.

Cancer research and treatment - 1 Apr 2026

Jung Sunwoo, Kim Ji-Won, Han Buhm

Abstract excerpt

PURPOSE: Although non-coding RNAs (ncRNAs) have often been implicated in various cancers, their causal roles in acute (AML) and chronic myeloid leukemia (CML) remain unclear. Here, we conducted a genome-wide two-sample Mendelian randomization (MR) study to investigate the causal effects of a comprehensive set of ncRNAs on AML and CML. MATERIALS AND METHODS: We used summary statistics of blood expression...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Leukemia, Myeloid, Acute

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to RNA, Untranslated

Source

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Identifiers

PMID: 40575950
DOI: 10.4143/crt.2025.377
PMCID: PMC13102300

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GMDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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