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Directed conversion of porcine extended pluripotent stem cells into trophoblast-like stem cells through modulation of conserved TGF-β and ERK signaling pathways

2026-02-07

Abstract excerpt

Trophoblast stem cells (TSCs) provide a tractable system for interrogating the signaling pathways that govern extraembryonic lineage commitment. Although trophoblast specification has been extensively characterized in humans and rodents, comparable tools and molecular frameworks remain poorly defined in pigs. Here, we identify defined biochemical conditions that enable the conversion of porcine extended pluripoten...

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Literature Corpus work
ab4974d4-f5a0-5a14-90c4-7377fcabf5f6
DOI
10.64898/2026.02.04.703856
Open publication

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Directed conversion of porcine extended pluripotent stem cells into trophoblast-like stem cells through modulation of conserved TGF-β and ERK signaling pathwaysDOI 10.64898/2026.02.04.703856
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