Article

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

2020-11-05

Abstract excerpt

Recently, efficient and long-term in vivo gene transfer by recombinant adeno-associated virus type 2 (rAAV) vectors has been demonstrated in a variety of tissues. Further improvement in vector titer and purity will expedite this in vivo exploration and provide preclinical information required for use in human gene therapy. In an effort to obtain higher titers, we constructed a novel AAV helper plasmid which utiliz...

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Literature Corpus work: ab2ea334-acf6-566e-8ed3-8f6c062800a8
DOI: 10.17615/b0s4-e007

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