Article

Polygenic risk scores as a marker for epilepsy risk across lifetime and after unspecified seizure events

2023-11-27

Abstract excerpt

A diagnosis of epilepsy has significant consequences for an individual but is often challenging in clinical practice. Novel biomarkers are thus greatly needed. Here, we investigated how common genetic factors (epilepsy polygenic risk scores, [PRSs]) influence epilepsy risk in detailed longitudinal electronic health records (EHRs) of > 360k Finns spanning up to 50 years of individuals’ lifetimes. Individuals with a...

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Literature Corpus work: ab19d41f-da60-52c0-9d6f-4a67b10a65d9
DOI: 10.1101/2023.11.27.23297542

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