Article
Bordetella pertussis autotransporter Vag8 binds human C1 esterase inhibitor and confers serum resistance.
PloS one - 1 Jan 2011
Marr Nico, Shah Nita R, Lee Rose, Kim Emma J, Fernandez Rachel C
Abstract excerpt
Bordetella pertussis employs numerous strategies to evade the immune system, including the ability to resist killing via complement. Previously we have shown that B. pertussis binds a complement regulatory protein, C1 esterase inhibitor (C1inh) to its surface in a Bvg-regulated manner (i.e. during its virulence phase), but the B. pertussis factor was not identified. Here we set out to identify the B. pertussis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
