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Article

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

4 Jul 2019

Abstract excerpt

Hundreds of cellular host factors are required to support dengue virus infection, but their identity and roles are incompletely characterized. Here, we identify human host dependency factors required for efficient dengue virus-2 (DENV2) infection of human cells. We focused on two, TTC35 and TMEM111, which we previously demonstrated to be required for yellow fever virus (YFV) infection and others subsequently...

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PMID: 31273220
DOI: 10.1038/s41598-019-45910-9

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