Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses

7 Nov 2011

Abstract excerpt

Negative-strand (NS) RNA viruses comprise many pathogens that cause serious diseases in humans and animals. Despite their clinical importance, little is known about the host factors required for their infection. Using vesicular stomatitis virus (VSV), a prototypic NS RNA virus in the family Rhabdoviridae, we conducted a human genome-wide siRNA screen and identified 72 host genes required for viral infection. Many...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Respiratory viral infections research
Share to Viral Infections and Vectors
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22065774
DOI: 10.1073/pnas.1113643108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA virusesPMID 22065774Read ↗

A Genome-Wide Small Interfering RNA Screen Identifies Host Factors Required for Vesicular Stomatitis Virus InfectionSemantic proximity Read ↗

Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function ScreenSemantic proximity Read ↗

Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from EndosomesSemantic proximity Read ↗

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) ProteinsSemantic proximity Read ↗

Role of RNA-binding proteins during the late stages of Flavivirus replication cycleSemantic proximity Read ↗

Pro-Viral and Anti-Viral Roles of the RNA-Binding Protein G3BP1Semantic proximity Read ↗

Comparative Loss-of-Function Screens Reveal ABCE1 as an Essential Cellular Host Factor for Efficient Translation of Paramyxoviridae and PneumoviridaeSemantic proximity Read ↗

Flaviviral RNAs: weapons and targets in the war between virus and hostSemantic proximity Read ↗

Picornavirus nonstructural proteins: emerging roles in virus replication and inhibition of host cell functionsSemantic proximity Read ↗

New World and Old World Alphaviruses Have Evolved to Exploit Different Components of Stress Granules, FXR and G3BP Proteins, for Assembly of Viral Replication ComplexesSemantic proximity Read ↗

Identification of RNA-Protein Interaction Networks Involved in the Norovirus Life CycleSemantic proximity Read ↗

The Viral Polymerase Complex Mediates the Interaction of vRNPs with Recycling Endosomes During SeV AssemblySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.