Article

Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX

2022-04-26

Abstract excerpt

Although picornaviruses are conventionally considered ‘nonenveloped’, members of multiple picornaviral genera are released nonlytically from infected cells in extracellular vesicles. The mechanisms underlying this process are poorly understood. Here, we describe interactions of the hepatitis A virus (HAV) capsid with components of host endosomal sorting complexes required for transport (ESCRT) that play an essenti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e0e405ff-c8ce-5acc-b19e-b1fcdc7bd197
DOI: 10.1101/2022.04.26.489493

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIXDOI 10.1101/2022.04.26.489493Read

Hepatitis Viruses Control Host Immune Responses by Modifying the Exosomal Biogenesis Pathway and CargoSemantic proximity Read

Hijacking host extracellular vesicle machinery by hepatotropic viruses: current understandings and future prospectsSemantic proximity Read

Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virusSemantic proximity Read

Hepatitis E virus egress and beyond – the manifold roles of the viral ORF3 proteinSemantic proximity Read

Intricate relationships between naked viruses and extracellular vesicles in the crosstalk between pathogen and hostSemantic proximity Read

Picornavirus infection induces temporal release of multiple extracellular vesicle subsets that differ in molecular composition and infectious potentialSemantic proximity Read

Bluetongue Virus Capsid Assembly and MaturationSemantic proximity Read

Coatomer protein complex I is required for efficient secretion of dengue virus non-structural protein 1Semantic proximity Read

Intracellular Trafficking of HBV ParticlesSemantic proximity Read

A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus UncoatingSemantic proximity Read

Cargo and biological properties of extracellular vesicles released from human adenovirus type 4-infected lung epithelial cellsSemantic proximity Read

Reovirus infection is regulated by NPC1 and endosomal cholesterol homeostasisSemantic proximity Read