Article

A large-scale genome-wide enrichment analysis identifies new trait-associated genes, pathways and tissues across 31 human phenotypes <sup>*</sup>

2017-07-08

Abstract excerpt

Genome-wide association studies (GWAS) aim to identify genetic factors that are associated with complex traits. Standard analyses test individual genetic variants, one at a time, for association with a trait. However, variant-level associations are hard to identify (because of small effects) and can be difficult to interpret biologically. “Enrichment analyses” help address both these problems by focusing on sets...

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Literature Corpus work: aaa26dbc-7589-5d01-91a4-be601602b040
DOI: 10.1101/160770

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