Article
Investigating the role of inflammatory biomarkers and incretins in the aetiology of type 2 diabetes and coronary heart disease using human genetics
2020-01-01
Abstract excerpt
Background: The relevance of inflammatory and incretin-related signalling pathways in the aetiology of cardiometabolic diseases is of considerable pharmacological interest but remains uncertain. Evidence from animal models and epidemiological studies point to a role for chronic inflammation for the pathophysiology of type 2 diabetes (T2D), with interleukin-6 (IL-6) proposed as a key player. Incretins such as gluca...
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Identifiers and source
- Literature Corpus work
- aa7b47fa-99a9-5c03-841f-940910ad49b2
- DOI
- 10.17863/cam.70467