Article

Photolytic degradation of Alzheimer's amyloid Aβ42-fibrils by sialic acid decorated glycodendrimers

2025-05-07

Abstract excerpt

<title>Abstract</title> <p>The formation of amyloid Aβ42-fibrils is linked to the pathology of cognitive dysfunction in Alzheimer's patients. There is a dire need for developing therapeutics to reverse Aβ42 fibrillation to stop or slow down the disease progression. Here, we report rationally designed sialic-acid functionalized porphyrin-cored first and second-generation dendrimers, synthesized using "click chemis...

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Literature Corpus work: aa772508-085b-5058-bfb3-d40caef55f39
DOI: 10.21203/rs.3.rs-6562396/v1

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Photolytic degradation of Alzheimer's amyloid Aβ42-fibrils by sialic acid decorated glycodendrimersDOI 10.21203/rs.3.rs-6562396/v1Read

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