Article

Aβ42 and ROS Dual-targeted Multifunctional Nanocomposite for Combination Therapy of Alzheimer’s Disease

2023-12-12

Abstract excerpt

Amyloid-β (Aβ) is prone to misfolding into neurotoxic aggregates that generate high levels of reactive oxygen species (ROS), leading to progressive oxidative damage and ultimately cell death. Therefore, simultaneous inhibition of Aβ aggregation and scavenging ROS may be a promising therapeutic strategy for alleviating Alzheimer’s disease pathology. Based on the previously developed antibody 1F12 that can target al...

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Literature Corpus work: 4ad2e047-2a7b-5a3d-bb29-03397dd0be19
DOI: 10.21203/rs.3.rs-3715133/v1

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