Article

Benchmarking PWM and SVM-based Models for Transcription Factor Binding Site Prediction: A Comparative Analysis on Synthetic and Biological Data

2025-03-23

Abstract excerpt

Transcription Factors (TFs) are essential regulatory proteins that control the cellular transcriptional states by binding to specific DNA sequences known as Transcription Factor Binding Sites (TFBSs) or motifs. Accurate TFBS identification is crucial for unraveling regulatory mechanisms driving cellular dynamics. Over the years, various computational approaches have been developed to model TFBSs, with Position Wei...

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Literature Corpus work: 7230c72f-5c8f-5253-a703-5375b107f884
DOI: 10.1101/2025.03.20.644354

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