Article

AmalgaMo: flexible DNA motif merging

2025-08-01

Abstract excerpt

<h4>Motivation</h4> Inference of candidate upstream regulators via motif enrichment analysis is a common step in the interpretation of genomic data. However, redundancy in motif databases can negatively impact predictive value, especially when relying on regression-based motif enrichment analysis. Although various forms of motif clustering have been used to mitigate problems caused by redundancy, an algorithm opt...

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Literature Corpus work: 13dfe6b5-7742-5073-b963-f03419da89f5
DOI: 10.1101/2025.07.29.667561

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