Article

Controlling the switch from neurogenesis to pluripotency during marmoset monkey somatic cell reprogramming with self-replicating mRNAs and small molecules

2020-05-24

Abstract excerpt

<h4>SUMMARY</h4> Induced pluripotent stem cells (iPSCs) hold enormous potential for the development of cell-based therapies for many currently incurable diseases. However, the safety and efficacy of potential iPSC-based treatments need to be verified in relevant animal disease models before their application in the clinic. Moreover, in order to reduce possible risks for the patients, it is necessary to use reprog...

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Literature Corpus work: aa3a2cd6-fb45-5ece-a861-55849f0fbb4a
DOI: 10.1101/2020.05.21.107862

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