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Short Tandem Repeat stutter_model_inferred from direct measurement of in vitro stutter noise

2016-07-21

Abstract excerpt

Short tandem repeats (STRs) are polymorphic genomic loci valuable for various applications such as research, diagnostics and forensics. However, their polymorphic nature also introduces noise during in vitro amplification, making them difficult to analyze. Although it is possible to overcome stutter noise by using amplification-free library preparation, such protocols are presently incompatible with single cell a...

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Literature Corpus work
a9f71346-ff69-5172-b1e0-3cf9671ef3a4
DOI
10.1101/065110
Open publication

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Short Tandem Repeat stutter_model_inferred from direct measurement of in vitro stutter noiseDOI 10.1101/065110
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