Article
Rapid multiplexed genotyping of simple tandem repeats using capture and high-throughput sequencing.
Human mutation - 1 Sept 2013
Guilmatre Audrey, Highnam Gareth, Borel Christelle, Mittelman David, Sharp Andrew J
Abstract excerpt
Although simple tandem repeats (STRs) comprise ~2% of the human genome and represent an important source of polymorphism, this class of variation remains understudied. We have developed a cost-effective strategy for performing targeted enrichment of STR regions that utilizes capture probes targeting the flanking sequences of STR loci, enabling specific capture of DNA fragments containing STRs for subsequent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.