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Caerin 1.1/1.9 disrupts growth and biofilms of carbapenem-resistant Klebsiella pneumoniae with a transcriptomic signature of translational and metabolic stress

2026-04-13

Abstract excerpt

<title>Abstract</title> <p> Carbapenem-resistant <italic>Klebsiella pneumoniae</italic> (CRKP) is a critical multidrug-resistant pathogen associated with limited therapeutic options and high mortality. The development of alternative antimicrobial strategies with novel mechanisms of action is urgently needed. In this study, we evaluated the antibacterial efficacy and mechanistic impact of a fixed 1:1 combinatio...

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Literature Corpus work
a9b2b62e-94b1-5274-8faf-73b3545021b8
DOI
10.21203/rs.3.rs-9232763/v1
Open publication

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Caerin 1.1/1.9 disrupts growth and biofilms of carbapenem-resistant Klebsiella pneumoniae with a transcriptomic signature of translational and metabolic stressDOI 10.21203/rs.3.rs-9232763/v1
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