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Reduced virulence and enhanced host adaption during antibiotics therapy: A story of a within-host carbapenem-resistant <i>Klebsiella pneumoniae</i> sequence type 11 evolution in a fatal scrotal abscess patient

2021-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Carbapenem-resistant Klebsiella pneumoniae (CRKP) has disseminated globally and become a major threat to human life. The sequence type (ST) 11 CRKP is a dominant clone in Asia, especially China, but how this clone evolves in vivo , then adapts to host and facilitates dissemination remain largely unknown. We analyzed the genomic dynamics of 4 ST11-CRKP isolates sequencially isolated from the ur...

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Literature Corpus work
d0976106-463b-5cab-bb9d-69efe37a9506
DOI
10.1101/2021.05.06.443049
Open publication

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Reduced virulence and enhanced host adaption during antibiotics therapy: A story of a within-host carbapenem-resistant <i>Klebsiella pneumoniae</i> sequence type 11 evolution in a fatal scrotal abscess patientDOI 10.1101/2021.05.06.443049
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