Phenotypic and Transcriptomic Characterization of Host-Associated Responses in a Carbapenem-Resistant Klebsiella pneumoniae ST11 Clinical Isolate.

doi:10.3390/pathogens15030282

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Article

Phenotypic and Transcriptomic Characterization of Host-Associated Responses in a Carbapenem-Resistant Klebsiella pneumoniae ST11 Clinical Isolate.

Pathogens (Basel, Switzerland) - 5 Mar 2026

Hua Miaomiao, Ji Jun, Wang Zhongyu, Li Jingjing, Cao Xiaoli

Abstract excerpt

Carbapenem-resistant Klebsiella pneumoniae (CRKP) sequence type 11 (ST11) is widely reported in Asia and represents an important clinical concern. Although antimicrobial resistance in ST11 isolates has been extensively investigated, less is known about the phenotypic characteristics and host-associated transcriptional responses of individual clinical isolates. In this study, we performed an in-depth...

Topics

Klebsiella pneumoniae
Klebsiella Infections
Humans
Animals
Gene Expression Profiling
Phenotype
Transcriptome
Virulence
Carbapenems
Host-Pathogen Interactions
Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Moths

Biofilms

Macrophages

Carbapenem-Resistant Enterobacteriaceae

Microbial Sensitivity Tests

Gene Expression Regulation, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 41901735
DOI: 10.3390/pathogens15030282
PMCID: PMC13029304

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41901735-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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