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Article

Redefinition of transmission clusters by accessing to additional diversity in Mycobacterium tuberculosis through long-read sequencing

2025-08-05

Abstract excerpt

<title>Abstract</title> <p> Whole-genome sequencing, supported on short-read-sequencing, has revolutionized the precision to track <italic>Mycobacterium tuberculosis</italic> (MTB) transmission. However, the complexity of the MTB genome (10% repetitive regions and 65% GC content) challenges short-read mapping and assembly, leading to the exclusion of certain genomic regions from the analysis. Long-read-sequenc...

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Literature Corpus work
a95d72ae-cb6b-5c87-bc2f-e46b9c56b7f6
DOI
10.21203/rs.3.rs-6046725/v2
Open publication

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Redefinition of transmission clusters by accessing to additional diversity in Mycobacterium tuberculosis through long-read sequencingDOI 10.21203/rs.3.rs-6046725/v2
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