Article

Neutrophils impose strong selective pressure against PfEMP1 variants implicated in cerebral malaria

2021-05-09

Abstract excerpt

Plasmodium falciparum, the deadliest form of human malaria, remains one of the major threats to human health in endemic regions. Its virulence is attributed to its ability to modify infected red blood cells (iRBC) to adhere to endothelial receptors by placing variable antigens known as PfEMP1 on the surface of the red cell. PfEMP1 expression on the red cell surface determines the cytoadhesive properties of the iRB...

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Literature Corpus work: a95196d1-4b22-5693-b761-0fffd5eff7f4
DOI: 10.1101/2021.05.09.443317

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