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Article

Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 Variants

1 Nov 2019

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31726028
DOI: 10.1016/j.chom.2019.10.012

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Related research

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Research trail→

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Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 VariantsPMID 31726028Read ↗

Protective immunity against severe malaria is associated with antibodies to a conserved repertoire of PfEMP1 variantsSemantic proximity Read ↗

Parasite features impeding malaria immunity: antigenic diversity, antigenic variation and poor immunogenicity.Semantic proximity Read ↗

Longitudinal analysis of naturally acquired antibodies to PfEMP1 CIDR domain variants and their association with malaria protectionSemantic proximity Read ↗

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Antibody responses to recombinant oligopeptides of PfEMP1 isolated from children infected with Plasmodium falciparumSemantic proximity Read ↗

Sequential, Ordered Acquisition of Antibodies to <i>Plasmodium falciparum</i> Erythrocyte Membrane Protein 1 DomainsSemantic proximity Read ↗

A principal target of human immunity to malaria identified by molecular population genetic and immunological analysesSemantic proximity Read ↗

Correlative humoral and cellular immunity to genetically attenuated malaria parasites in humansSemantic proximity Read ↗

Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria.Semantic proximity Read ↗

In vivo, in vitro, and in silico studies suggest a conserved immune module that regulates malaria parasite transmission from mammals to mosquitoesSemantic proximity Read ↗

Immune effector mechanisms in malariaSemantic proximity Read ↗

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