Article
Multiple adhesive phenotypes linked to rosetting binding of erythrocytes in Plasmodium falciparum malaria.
Infection and immunity - 1 Jun 1998
Fernandez V, Treutiger C J, Nash G B, Wahlgren M
Abstract excerpt
The cerebral form of severe malaria is associated with excessive intravascular sequestration of Plasmodium falciparum-infected erythrocytes (PRBC). Retention and accumulation of PRBC may lead to occlusion of brain microvessels and direct the triggering of acute pathologic changes. Here we report...
Topics
- Animals
- Antigens, Surface
- Blood Proteins
- CD36 Antigens
- Cell Adhesion
- Clone Cells
- Endothelium, Vascular
- Erythrocytes
- Humans
- Kenya
- Ligands
- Malaria, Falciparum
- Phenotype
- Plasmodium falciparum
- Protozoan Proteins
- Receptors, Cell Surface
- Rosette Formation
- Selection, Genetic