Article

Vitamin C administration by intravenous infusion increases tumour ascorbate content in patients with colon cancer: a clinical intervention study

2020-08-25

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> The use of high dose ascorbate infusions in cancer patients is widespread, but without evidence of efficacy. Several mechanisms whereby ascorbate could affect tumour progression have been proposed, including (i) the localised generation of cytotoxic quantities of H2O2, (ii) ascorbate-dependent activation of the 2-oxoglutarate-dependent dioxygenases that control...

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Literature Corpus work: a92b022b-1e06-503b-ad3e-4dc9ca1a3fb3
DOI: 10.21203/rs.3.rs-65137/v1

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