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Exercise serum promotes DNA damage repair and upregulates DNA repair gene <i>PNKP</i> in colon cancer cells

2025-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Exercise protects against colon cancer progression, but the underlying biological mechanisms remain incompletely understood. One proposed mechanism is the release of bioactive molecules into the interstitium and systemic circulation during exercise, which may act directly on precancerous or tumour cells to suppress DNA damage, inhibit proliferation, and preserve genomic stability. Here, we evalu...

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Literature Corpus work
929451a1-6bb5-5388-93f9-cf857596e49c
DOI
10.1101/2025.06.26.659251
Open publication

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Exercise serum promotes DNA damage repair and upregulates DNA repair gene <i>PNKP</i> in colon cancer cellsDOI 10.1101/2025.06.26.659251
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