Article

Resting State Functional Connectivity is Decreased Globally Across the <i>C9orf72</i> Mutation Spectrum

2020-08-11

Abstract excerpt

A repeat expansion mutation in the C9orf72 gene causes amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), or symptoms of both, and has been associated with gray and white matter changes in brain MRI scans. We used graph theory to examine the network properties of brain function at rest in a population of mixed-phenotype C9orf72 mutation carriers (C9+). Twenty-five C9+ subjects (presymptomatic, or...

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Literature Corpus work: a9156c0d-5d78-528f-bf4f-3a31fa247c7a
DOI: 10.1101/2020.08.10.20171991

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