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Gut Microbiota Influences Experimental Outcomes in Mouse Models of Colorectal Cancer

7 Nov 2019

Abstract excerpt

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Mouse models are a valuable resource for use throughout the development and testing of new therapeutic strategies for CRC. Tumorigenesis and response to therapy in humans and mouse models alike are influenced by the microbial communities that colonize the gut. Differences in the composition of the gut microbiota can confound...

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PMID: 31703321
DOI: 10.3390/genes10110900

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