Article

Two variance component model improves genetic prediction in family data sets

2015-03-17

Abstract excerpt

Genetic prediction based on either identity by state (IBS) sharing or pedigree information has been investigated extensively using Best Linear Unbiased Prediction (BLUP) methods. Such methods were pioneered in the plant and animal breeding literature and have since been applied to predict human traits with the aim of eventual clinical utility. However, methods to combine IBS sharing and pedigree information for ge...

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Literature Corpus work: a8c3a170-8e88-5bdb-94b8-2c93ee8929b3
DOI: 10.1101/016618

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