Article

Estimating variance components in population scale family trees

2018-01-30

Abstract excerpt

The rapid digitization of genealogical and medical records enables the assembly of extremely large pedigree records spanning millions of individuals and trillions of pairs of relatives. Such pedigrees provide the opportunity to investigate the sociological and epidemiological history of human populations in scales much larger than previously possible. Linear mixed models (LMMs) are routinely used to analyze extrem...

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Literature Corpus work: 744d0d4f-9657-5975-add4-9498eebb59f6
DOI: 10.1101/256396

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