Article
Complex traits and candidate genes: estimation of genetic variance components across multiple genetic architectures.
G3 (Bethesda, Md.) - 30 Aug 2023
Feldmann Mitchell J, Covarrubias-Pazaran Giovanny, Piepho Hans-Peter
Abstract excerpt
Large-effect loci-those statistically significant loci discovered by genome-wide association studies or linkage mapping-associated with key traits segregate amidst a background of minor, often undetectable, genetic effects in wild and domesticated plants and animals. Accurately attributing mean differences and variance explained to the correct components in the linear mixed model analysis is vital for selecting...
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