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Complex traits and candidate genes: estimation of genetic variance components across multiple genetic architectures.

G3 (Bethesda, Md.) - 30 Aug 2023

Feldmann Mitchell J, Covarrubias-Pazaran Giovanny, Piepho Hans-Peter

Abstract excerpt

Large-effect loci-those statistically significant loci discovered by genome-wide association studies or linkage mapping-associated with key traits segregate amidst a background of minor, often undetectable, genetic effects in wild and domesticated plants and animals. Accurately attributing mean differences and variance explained to the correct components in the linear mixed model analysis is vital for selecting...

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Models, Genetic
Chromosome Mapping
Genome
Genome-Wide Association Study
Multifactorial Inheritance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 37405459
DOI: 10.1093/g3journal/jkad148
PMCID: PMC10468314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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