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Genetic evidence for protective effects of angiotensin converting enzyme against Alzheimer's disease but not other neurodegenerative diseases

2024-01-31

Abstract excerpt

Genetic evidence has supported a protective effect of cerebral angiotensin converting enzyme (ACE) against Alzheimer’s disease (AD). However, it is unclear whether this is mediated through blood pressure and extends to other neurodegenerative diseases. We performed genetic colocalization investigating an effect of cortical ACE expression on AD risk. We further investigated whether any effect of ACE expression is m...

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Literature Corpus work
a8aeaccb-da5f-5e16-a7f5-54e1fd242068
DOI
10.22541/au.170670111.10019848/v1
Open publication

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Genetic evidence for protective effects of angiotensin converting enzyme against Alzheimer's disease but not other neurodegenerative diseasesDOI 10.22541/au.170670111.10019848/v1
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