Article

The tRNA Gm18 Methyltransferase TARBP1 Promotes Hepatocellular Carcinoma Progression via Metabolic Reprogramming of Glutamine

2023-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Cancer cells rely on metabolic reprogramming to sustain the prodigious energetic requirements for rapid growth and proliferation. Glutamine metabolism is frequently dysregulated in cancers and is being exploited as a potential therapeutic target. In current study, we identified TARBP1 (TAR (HIV-1) RNA Binding Protein 1) as a novel driver gene critical for glutamine metabolic reprogramming in tum...

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Literature Corpus work: a8ad4d90-4f68-5771-a20e-c6ce41c3c0e0
DOI: 10.1101/2023.06.14.544902

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