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Orally Administered EC16 Nanoparticles Attenuate Periodontitis and Cross the Blood–Brain Barrier to Modulate Neuroinflammatory Responses: A Pilot Murine Model Study

2026-05-13

Abstract excerpt

Periodontal disease (PD) affects a large proportion of adults and is increasingly associated with systemic inflammation and neurodegenerative risk. However, current therapies have limited efficacy in disrupting biofilms and modulating systemic responses. In this pilot study, we evaluated nanoparticles (NPs) of epigallocatechin-3-gallate-palmitate (EGCG-palmitate or EC16), a lipid-soluble derivative of epigallocate...

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Literature Corpus work
a886f7ae-41cb-5368-9105-1350b8e1c2fb
DOI
10.20944/preprints202603.2528.v2
Open publication

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Orally Administered EC16 Nanoparticles Attenuate Periodontitis and Cross the Blood–Brain Barrier to Modulate Neuroinflammatory Responses: A Pilot Murine Model StudyDOI 10.20944/preprints202603.2528.v2
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