Article
Facile engineering of resveratrol nanoparticles loaded with 20(S)-protopanaxadiol for the treatment of periodontitis by regulating the macrophage phenotype.
Nanoscale - 4 May 2023
Huangfu Huimin, Du Shulin, Zhang Hao, Wang Hanchi, Zhang Yi, Yang Zhen, Zhang Xinwei, Ren Sicong, Chen Siyu, Wang Cuizhu, Zhang Yidi, Zhou Yanmin
Abstract excerpt
Periodontitis is an inflammatory disease, mainly caused by the formation of a subgingival plaque biofilm. In recent years, growing attention has been paid to immunotherapy in the treatment of periodontitis, and the importance of communal intervention associated with macrophage polarization was emphasized. Herein, resveratrol (RES) and 20(S)-protopanaxadiol (PPD) were successfully self-assembled into RES@PPD...
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