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Orally Administered EC16 Nanoparticles Attenuate Periodontitis and Cross the Blood–Brain Barrier to Modulate Neuroinflammatory Responses

2026-04-01

Abstract excerpt

Periodontal disease (PD) affects a large proportion of adults and is increasingly associated with systemic inflammation and neurodegenerative risk. However, current therapies have limited efficacy in disrupting biofilms and modulating systemic responses. In this pilot study, we evaluated epigallocatechin-3-gallate-palmitate (EGCG-palmitate or EC16) nanoparticles (NPs), a lipid-soluble derivative of epigallocatechi...

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Literature Corpus work
3e923537-e6f5-5d0d-81fe-4d71ab533d75
DOI
10.20944/preprints202603.2528.v1
Open publication

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