Article

Mouth gel containing phthalocyanine derivative attenuates TNF-α through NF-κB inhibition in experimental periodontitis

2024-04-02

Abstract excerpt

<h4>Background: </h4> Tumor necrosis factor alpha (TNF-α) is a major cytokine involved in periodontal disease pathogenesis due to its ability to modulate inflammatory cytokine production and cell influx in tooth-supporting tissues. Therefore, TNF-α is an excellent target for limiting the inflammatory process and avoiding alveolar bone resorption and tooth loss. Objective This study investigated the activity and a...

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Literature Corpus work: c2989457-4007-5538-b6da-e0fd45abfe8d
DOI: 10.21203/rs.3.rs-4181301/v1

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