Article

Rare genetic variants in the endocannabinoid system genes <i>CNR1</i> and <i>DAGLA</i> are associated with neurological phenotypes in humans

2017-07-25

Abstract excerpt

Rare genetic variants in the core endocannabinoid system genes CNR1 , CNR2 , DAGLA , MGLL and FAAH were identified in molecular testing data from up to 6.032 patients with a broad spectrum of neurological disorders. The variants were evaluated for association with phenotypes similar to those observed in the orthologous gene knockouts in mice. Heterozygous rare coding variants in CNR1 , which encodes the type...

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Literature Corpus work: a87d37b3-240d-5f34-860f-069ae257f756
DOI: 10.1101/168435

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