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Article

Single nucleotide polymorphisms in the cannabinoid CB2 receptor: Molecular pharmacology and disease associations.

British journal of pharmacology - 1 Aug 2024

Foyzun Tahira, Whiting Maddie, Velasco Kate K, Jacobsen Jessie C, Connor Mark, Grimsey Natasha L

Abstract excerpt

Preclinical evidence implicating cannabinoid receptor 2 (CB2) in various diseases has led researchers to question whether CB2 genetics influence aetiology or progression. Associations between conditions and genetic loci are often studied via single nucleotide polymorphism (SNP) prevalence in case versus control populations. In the CNR2 coding exon, ~36 SNPs have high overall population prevalence (minor allele...

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PMID: 38802979
DOI: 10.1111/bph.16383

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