Rare<i>CRHR2</i>and<i>GRM8</i>variants identified as candidate factors associated with eating disorders in Japanese patients

Abstract excerpt

Eating disorders (EDs) are a type of psychiatric disorder characterized by pathological eating and related behavior and considered to be highly heritable. The purpose of this study was to explore rare variants expected to display biological functions associated with the etiology of EDs. We performed whole exome sequencing (WES) of affected sib-pairs corresponding to disease subtype through their lifetime and their...

Topics

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• Bipolar Disorder
• Exome Sequencing
• Family
• Genetic Linkage
• Genome-Wide Association Study
• High-Throughput Nucleotide Sequencing
• Receptors, Corticotropin-Releasing Hormone
• Receptors, G-Protein-Coupled

Identifiers and source

Literature Corpus work

71a8eadd-21a5-5d9c-a934-8943358d37dc

DOI

10.1101/2023.08.24.23294455