Article

Growth of tumor emboli within a vessel model reveals dependence on the magnitude of mechanical constraint

2020-07-06

Abstract excerpt

<h4>ABSTRACT</h4> Tumor emboli – aggregates of tumor cell within vessels – pose a clinical challenge as they are associated with increased metastasis and tumor recurrence. When growing within a vessel, tumor emboli are subject to a unique mechanical constraint provided by the tubular geometry of the vessel. Current models of tumor emboli use unconstrained multicellular tumor spheroids, which neglect this mechanic...

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Literature Corpus work: a85f5163-7b0c-5db2-b4f9-118b1edadf5a
DOI: 10.1101/2020.07.06.190447

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