Article

Expression and function of <i>TRK-B</i> and <i>BDNF</i> in human neuroblastomas

1994-01-01

Abstract excerpt

There is considerable interest in the role of the TRK family of neuotrophin receptors in regulating growth and differentiation in normal and neoplastic nerve cells. A neuroblastoma is a common pediatric tumor derived from the neural crest, and the majority of favorable neuroblastomas express a high level of TRK-A mRNA. However, little is known about the expression or function of TRK-B in these tumors. TRK-B encode...

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Literature Corpus work: a858e1da-6b7b-58d4-b755-5059ca65141a
DOI: 10.1128/mcb.14.1.759-767.1994

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