Article

Transcriptional Regulation of Microglial Metabolic and Activation States by P2RY12

2025-07-25

Abstract excerpt

Microglia are the resident immune cells of the CNS. Under homeostatic conditions, Microglia play critical roles orchestrating synaptic pruning, debris clearance and dead cells removals. In disease, they are powerful mediators of neuroinflammation, as they rapidly respond to injury or infection within the CNS by altering their morphology, proliferating, and releasing cytokines and other signaling molecules. Underst...

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Literature Corpus work: a84c0a72-25a9-57a3-a1b2-e132fa1cbec7
DOI: 10.1101/2025.07.21.665960

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