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Disulfide-rich, cyclic peptides from <i>Clitoria ternatea</i> protect against β-amyloid toxicity and oxidative stress in transgenic <i>Caenorhabditis elegans</i>

2021-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Neurotoxic aggregation of β-amyloid (Aβ) peptide is a hallmark of Alzheimer’s disease and increased reactive oxygen species (ROS) is known to be associated with this. Here, we report neuroprotective effects of disulfide-rich, circular peptides from Clitoria ternatea on Aβ-induced toxicity in transgenic Caenorhabditis elegans . We show that cyclotide-rich fractions from different plant tissues...

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Literature Corpus work
a7f98b72-eb0a-5d0e-aac4-83b1529405ce
DOI
10.1101/2021.02.07.430179
Open publication

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Disulfide-rich, cyclic peptides from <i>Clitoria ternatea</i> protect against β-amyloid toxicity and oxidative stress in transgenic <i>Caenorhabditis elegans</i>DOI 10.1101/2021.02.07.430179
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