Article

Transcriptomic response of <i>Caenorhabditis elegans</i> expressing human Aβ <sub>42</sub> gene treated with Salvianolic acid A

2020-05-30

Abstract excerpt

Alzheimer’s disease (AD) is a brain disease attributed to the accumulation of extracellular senile plaques comprising β-amyloid peptide (Aβ). In this study, a global transcriptomic analysis of the response of transgenic Caenorhabditis elegans worms expressing full length human Aβ 42 gene towards Salvianolic acid A (Sal A) was analysed. Antioxidant response genes, namely gst-4 , gst-10 , spr-1 and trxr-2 , we...

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Literature Corpus work: ec78674e-1872-5aa2-8e82-4dfffb822b2a
DOI: 10.1101/2020.05.28.120485

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