Article

Single cell landscape of sex differences in the different courses of multiple sclerosis

2024-06-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> One of the major challenges in addressing multiple sclerosis is to understand its progression trajectory. The pathological process transitions from acute phases predominantly driven by inflammation to progressive clinical profiles where neurodegeneration takes precedence. It is known that sex plays a crucial role in this heterogeneity; females are two to three times more lik...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a7e983bf-5f86-5caa-8b56-90ae46e1b4e6
DOI: 10.1101/2024.06.15.599139

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single cell landscape of sex differences in the different courses of multiple sclerosisDOI 10.1101/2024.06.15.599139Read

Single cell landscape of sex differences in the progression of multiple sclerosisSemantic proximity Read

A Deep Transcriptome Meta-Analysis Reveals Sex-based Molecular Differences in Multiple SclerosisSemantic proximity Read

A Deep Transcriptome Meta-Analysis Reveals Sex Differences in Multiple SclerosisSemantic proximity Read

A deep transcriptome meta-analysis reveals sex differences in multiple sclerosisSemantic proximity Read

Sex differences in progressive multiple sclerosis brain gene expression in oligodendrocytes and OPCsSemantic proximity Read

A Case of Double Standard: Sex Differences in Multiple Sclerosis Risk FactorsSemantic proximity Read

Comparing Single-Cell Transcriptomes of Blood and Cerebrospinal Fluid Leukocytes in Multiple SclerosisSemantic proximity Read

Sex and Gender Differences in Neurodegenerative Diseases: Challenges for Therapeutic OpportunitiesSemantic proximity Read

Sex-Specific Cross Tissue Meta-Analysis Identifies Immune Dysregulation in Women with Alzheimer's DiseaseSemantic proximity Read

Human disease-specific cell signatures in non-lesional tissue in Multiple Sclerosis detected by single-cell and spatial transcriptomicsSemantic proximity Read

Transcriptomic Profile Reveals Gender-Specific Molecular Mechanisms Driving Multiple Sclerosis ProgressionSemantic proximity Read

Sex-aware causal inference assessment of the immune system in complex neurodegenerative diseases.Semantic proximity Read