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Article

Sex and Gender Differences in Neurodegenerative Diseases: Challenges for Therapeutic Opportunities

28 Mar 2023

Abstract excerpt

The term "neurodegenerative diseases" (NDs) identifies a group of heterogeneous diseases characterized by progressive loss of selectively vulnerable populations of neurons, which progressively deteriorates over time, leading to neuronal dysfunction. Protein aggregation and neuronal loss have been considered the most characteristic hallmarks of NDs, but growing evidence confirms that significant dysregulation of...

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PMID: 37047320
DOI: 10.3390/ijms24076354

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