Article

Cell fate specification and conversion generate foveolar cone subtype patterning in human retinal organoids

2023-01-29

Abstract excerpt

The mechanisms that generate patterns of cell types unique to humans are poorly understood. In the central region of the human retina, the high-acuity foveola is notable, in part, for its dense packing of green (M) and red (L) cones and absence of blue (S) cones. To identify mechanisms that promote M/L and suppress S cone patterning in the foveola, we examined human fetal retinas and differentiated human retinal o...

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Literature Corpus work: a7be7d57-7047-57f2-ba06-b683c9a4806b
DOI: 10.1101/2023.01.28.526051

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