Article

Spatiotemporal specification of human green and red cones

2021-03-31

Abstract excerpt

Trichromacy is unique to primates among mammals, enabled by blue (short/S), green (medium/M), and red (long/L) cones. In humans and Old World monkeys, cones make a poorly understood choice between M and L cone subtype fates. To determine mechanisms specifying M and L cones, we developed an approach to visualize expression of the highly similar M - and L - opsin mRNAs. M - opsin , but not L - opsin , was obs...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 78133410-7e53-5fb2-bca6-3b2fbf7f4dff
DOI: 10.1101/2021.03.30.437763

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatiotemporal specification of human green and red conesDOI 10.1101/2021.03.30.437763Read

Retinoic acid signaling regulates spatiotemporal specification of human green and red conesSemantic proximity Read

Thyroid hormone signaling specifies cone subtypes in human retinal organoidsSemantic proximity Read

Cell fate specification and conversion generate foveolar cone subtype patterning in human retinal organoidsSemantic proximity Read

Spatial and temporal expression of short, long/medium, or both opsins in human fetal conesSemantic proximity Read

Single-cell RNA-seq analysis maps the development of human fetal retinaSemantic proximity Read

Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate RetinaSemantic proximity Read

Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3): Role in Retinal Development and DiseaseSemantic proximity Read

The nuclear receptor NR2E3 plays a role in human retinal photoreceptor differentiation and degeneration.Semantic proximity Read

A single-cell transcriptome atlas of the aging human and macaque retinaSemantic proximity Read

Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related featuresSemantic proximity Read

Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate.Semantic proximity Read

Expression of Photoreceptor-Specific Nuclear Receptor NR2E3 in Rod Photoreceptors of Fetal Human RetinaSemantic proximity Read